A proven, unique, non-invasive method for rapid treatment of chronic intractable pain

 Who is it for?
Scrambler Therapy is a new electroanalgesia methodology specifically studied for neuropathic and oncologic pain, and in general for pain non-responsive to other types of drugs and forms of electroanalgesia. Scrambler Therapy is a stand-alone medical electroanalgesia device, and does not require combinations with other analgesic therapies.

Scrambler Therapy ® is Non-invasive
During the development of Scrambler Therapy, artificial neurons were developed to transmit to the C.N.S. information recognizable as "self" and "non pain" in a non-invasive manner through surface C receptors. Compared to the conventional electro-analgesia, the active principle is not to inhibit pain transmission (through A-beta fiber excitation), but to substitute pain information with synthetic "non pain" information. In this way the pain is eliminated immediatly, and over time (on average 10 treatments) this producing a process of healing from chronic pain, thus giving longevity to the pain relief.
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How Scrambler Therapy ® Works?
There are various protocols according to different types of pain treated. In chronic benign pain caused by cures, such as for example CIPN, a treatment cycle is enough for a long period of wellbeing. In oncologic pain due to the presence of metastasis, after the initial treatment cycle further treatments should be carried out whenever pain re-emerges.

What are the success possibilities?
In general, if a specifically trained operator carries out the treatment, chances of success are very high. In the worst case around 70-80%, however they can be higher than 90%. The physician can make a more detailed forecast after a consultation.

Which are the effects of combinations with other analgesic therapies?
The usage of anticonvulsants for analgesic purposes generally calls for a higher number of treatments, needed for the weaning. The first five treatment with anticonvulsant can provide unstable result , that return to normal with continue the treatment cycle.

The protocol for patients who use anticonvulsant typically includes 10 treatments + those needed for  weaning. The frequency of treatment remains unchanged. It is also possible to continue the anticonvulsants analgesic therapy, however in this case results are not as good or insufficient, and relapse is quicker.

From study-phase data the combination with Ketamine is incompatible since it seems to block the analgesic efficacy of the treatment.  The normal analgesic effect of the treatment after the patient stops taking Ketamine is still unknown. Similar suspicions exist also for muscle relaxants, which in combination with this therapy could also cause minor side effects.

Some centers of reference

Clinical Trials.



U.S. DIS&L Division